Berikut hasil lengkap pekan pembuka Liga Premier Inggris 2021/22 (dalam WIB, tuan rumah disebut pertama):
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Sabtu (14/8) dini hari Brentford 2 - Arsenal 0 (Sergi Canos 22', Christian Norgaard 73')
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Sabtu (14/8) malam s.d. Minggu (15/8) dini hari Manchester United 5 - Leeds United 1 (Bruno Fernandes 30', 54', 60', Mason Greenwood 52', Fred 68'; Luke Ayling 49')Burnley 1 - Brighton & Hove Albion 2 (James Tarkowski 2'; Neal Maupay 73', Alexis Mac Allister 78')Chelsea 3 - Crystal Palace 0 (Marcos Alonso 27', Christian Pulisic 40', Trevor Chalobah 58')Everton 3 - Southampton 1 (Richarlison 47', Abdoulaye Doucoure 76', Dominic Calvert-Lewin 81'; Adam Armstrong 22')Leicester City 1 - Wolverhampton 0 (Jamie Vardy 41')Watford 3 - Aston Villa 2 (Emmanuel Dennis 10', Ismaila Sarr 42', Cucho Hernandez 67'; John McGinn 70', Danny Ings p-90+7')Norwich City 0 - Liverpool 3 (Diogo Jota 26', Roberto Firmino 65', Mohamed Salah 74')
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Minggu (15/8) malam Newcastle United 2 - West Ham 4 (Callum Wilson 5', Jacob Murphy 40'; Aaron Cresswell 18', Said Benrahma 53', Tomas Soucek 63', Michail Antonio 66')Tottenham 1 - Manchester City 0 (Son Heung-min 55')
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